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PRP vs. PRF: What’s the Difference and Which One Delivers More Value?

Westrick clinic prf platelet rich fibrin westrick clinic

In the world of regenerative aesthetics, platelet-based therapies have emerged as powerful tools to restore youthfulness and regenerate hair growth naturally. Two of the most talked-about treatments; PRP (Platelet-Rich Plasma) and PRF (Platelet-Rich Fibrin) share a similar origin but differ in how they’re processed and what they deliver.

If you’re wondering which is more effective, scientifically validated, and worth the investment, let’s break down PRP vs PRF and highlight what the research and real-world results say.

What Is PRP (Platelet-Rich Plasma)?

PRP is a regenerative treatment derived from a small sample of your blood. After being spun in a high-speed centrifuge, the plasma is separated out and concentrated with platelets / cells rich in growth factors that signal tissue repair and collagen regeneration.

What Is PRF (Platelet-Rich Fibrin)?

PRF is the next generation of PRP and arguably a more advanced and effective version. It’s created using a slower centrifugation process and without anticoagulants, preserving white blood cells, stem cells, and fibrin matrix along with platelets.

Unlike PRP, which is a liquid, PRF has a gel-like consistency that forms a scaffold, allowing for longer and slower release of growth factors over time.

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Sue West RN Registered Nurse, Co-Founder
Sue West is a Registered Nurse with 25+ years of clinical experience and Co-Founder of Westrick Clinic in Lacombe, Alberta. Certified in NeoGen nitrogen plasma therapy since 2023, she specializes in non-surgical medical aesthetics, pelvic floor therapy, and skin rejuvenation. Clients travel from across Alberta for their treatments.